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Pharmacogenomics in Clinical Practice: A Practical Guide to Genotype-Guided Dosing, Drug Response, and Precision Prescribing by Adrian Wellcroft

Pharmacogenomics in Clinical Practice: A Practical Guide to Genotype-Guided Dosing, Drug Response, and Precision Prescribing

by Adrian Wellcroft
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Book cover type: Paperback
  • ISBN13: 9798198037793
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Independently Published
  • Publisher Imprint: Independently Published
  • Publication Date:
  • Pages: 428
  • Original Price: USD 185.56
  • Language: English
  • Edition: N/A
  • Item Weight: 985 grams
  • BISAC Subject(s): Pharmacy

Move from genotype results to evidence-aware medication decisions with a clear, clinically grounded framework.

Pharmacogenomics in Clinical Practice: Prescribing by Genotype is a professional textbook for clinicians, pharmacists, advanced trainees, and health science learners who need a structured way to connect genetic variation with medication response. Instead of treating pharmacogenomic reports as isolated lab results, this book explains how variants, phenotypes, medication pathways, evidence frameworks, and decision support tools come together in real prescribing contexts.

Organized from foundational genetics through major gene-medication pairs, specialty applications, implementation science, health equity, and future precision prescribing, it gives readers a practical route through one of the most important areas of individualized medicine. The content is written for education and professional learning, supporting careful interpretation without replacing institutional protocols, current guidelines, or clinician judgment.

Inside, you will:

  • Build a working foundation in genetic variation, metabolizer phenotypes, pharmacokinetics, and pharmacodynamics.
  • Understand key enzyme, transporter, and HLA-related concepts used in medication safety discussions.
  • Interpret laboratory reports with greater confidence by connecting variants, phenotypes, and prescribing considerations.
  • Explore major application areas including cardiology, psychiatry, oncology, infectious disease, anesthesia, transplantation, and program implementation.
  • Strengthen awareness of evidence grading, panel design, decision support, ancestry, and health equity considerations.
  • Apply clinical pearl-style learning to reinforce practical, point-of-care reasoning.
  • Prepare for the future of precision prescribing through coverage of whole-genome sequencing, artificial intelligence, polygenic scores, and multi-omics integration.
Designed as an educational reference, this book is ideal for readers who want a serious, clinically oriented guide to pharmacogenomic thinking. Add it to your medical, pharmacy, or health science library as a focused resource for understanding how genomics is shaping modern medication decision-making.

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