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Plasma Membrane Shaping by Shiro Suetsugu

Plasma Membrane Shaping

by Shiro Suetsugu
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Book cover type: Paperback
  • ISBN13: 9780323899116
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Academic Press
  • Publisher Imprint: Academic Press
  • Publication Date:
  • Pages: 468
  • Original Price: USD 200.0
  • Language: English
  • Edition: N/A
  • Item Weight: 950 grams
  • BISAC Subject(s): Life Sciences / Cell Biology

Plasma Membrane Shaping summarizes current knowledge on how cells shape their membrane. Organized in four sections, the book opens with a broad overview of the plasma membrane, its composition, usual shapes and substructures, Actin/WASP/arp2/3 structures, BAR domains, and Ankyrin repeat domains, dynamin, and phospholipid signaling. Other sections cover the shaping of the plasma membrane for transport processes, discussions on exosomes, microvesicles, and endosomes, clathrin-coated pits, caveolae, and other endocytic pits, membrane deformation for cell movement, and some of the most current dry and wet lab research techniques to investigate cellular membrane shaping.

This is an ideal resource for new researchers coming into this area as well as for graduate students. The methods section will be of interest to both microscopists and computer scientists dedicated to the visualization, data collection, and analysis of plasma membrane shaping experiments.

Suetsugu, Shiro: - Dr. Suetsugu is currently Professor at Nara Institute of Science and Technology, Japan. He received his Ph.D and M.Sc in Cell Biology from the Department of Biochemistry and Biophysics, Graduate school of Sciences, The University of Tokyo. His research is focused on the cellular plasma membrane and its essential role of distinguishing the inside and the outside of the cells. He and his team focus on the mechanisms connecting the membrane to the cytoskeleton, and the membrane-binding proteins connecting the membrane to the intracellular and intercellular signaling for varieties of cellular functions including proliferation and morphological changes. They pioneered the membrane shaping protein of the plasma membrane and proposed the mechanisms of the membrane shaping. Notably, they contributed to the mechanisms of the concept of membrane shaping by the proteins having the BAR domains including the I-BAR domain. Throughout his career, Dr. Suetsugu received awards international and national awards such as FEBS Letters Young Group Leader Award, the Young Scientists' Prize by the Minister of Education, Culture, Sports, Science and Technology, Young Investigator Award, the Japanese Biochemical Society, and the 2015 Kazato Prize.

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