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Polimorfismi genici delle citochine in pazienti iracheni affetti da epatite virale by Osama Al-Saffar

Polimorfismi genici delle citochine in pazienti iracheni affetti da epatite virale

by Osama Al-Saffar , Ali Ad'hiah
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Book cover type: Paperback
  • ISBN13: 9786208008444
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Edizioni Sapienza
  • Publisher Imprint: Edizioni Sapienza
  • Publication Date:
  • Pages: 132
  • Original Price: GBP 39.06
  • Language: Italian
  • Edition: N/A
  • Item Weight: 186 grams
  • BISAC Subject(s): Life Sciences / Genetics & Genomics

L'epatite � un'infiammazione del fegato causata pi� comunemente da uno dei cinque tipi di virus dell'epatite: A, B, C, D ed E. Questi tipi sono particolarmente preoccupanti a causa del carico di malattia e di mortalit� che causano e del potenziale di epidemie e diffusione epidemica in tutto il mondo, in particolare i tipi B (HBV) e C (HCV). Pertanto, il presente studio ha mirato a indagare l'associazione tra i livelli sierici di cinque citochine (IL-2, IL-4, IL-10, TNF-α e IFN-γ) e i loro polimorfismi genici definiti mediante reazione a catena della polimerasi con primer specifici per sequenza (SSP-PCR) in 11 posizioni (IL2-330, IL2+166, IL4-1098, IL4-590, IL4+33, IL10-1082, IL10-819, IL10-592, TNF-308, TNF-238 e IFNγ+874) in campioni di pazienti iracheni infetti da HBV e HCV, al fine di identificare marcatori immunogenetici specifici (SNP delle citochine) che potrebbero essere associati alle infezioni da HBV e HCV.

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