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Prevalenza di malattia renale nei bambini con infezione da HIV-1 al KNH di Nairobi by David Galgallo

Prevalenza di malattia renale nei bambini con infezione da HIV-1 al KNH di Nairobi

by David Galgallo , Ruth Nduati , Elizabeth Obimbo
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Book cover type: Paperback
  • ISBN13: 9786208564872
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Edizioni Sapienza
  • Publisher Imprint: Edizioni Sapienza
  • Publication Date:
  • Pages: 60
  • Original Price: USD 41.0
  • Language: Italian
  • Edition: N/A
  • Item Weight: 96 grams
  • BISAC Subject(s): General

Il 60% dei pazienti con HIV/AID sviluppa una qualche forma di patologia renale. La proteinuria può essere la prima manifestazione clinica della nefropatia da HIV. Abbiamo condotto un'indagine trasversale tra i bambini con infezione da HIV per determinare la prevalenza della malattia renale. Sono stati reclutati 87 soggetti. Quarantasei (52,8%) erano femmine e 41 (47,1%) maschi. L'età variava da 18 mesi a 13 anni, con un'età mediana di 60 mesi. Complessivamente, il 35,6% dei pazienti aveva un'evidenza di nefropatia basata sulla presenza di proteinuria persistente e/o di un'anormale velocità di filtrazione glomerulare. La proteinuria è stata riscontrata in 28 (32,2%) dei soggetti e la proteinuria persistente in 14 (16,1%) soggetti. Quarantaquattro (50,6%) dei soggetti si trovavano nello stadio clinico OMS 3 della malattia, 17 (19,5%) nello stadio 2, 14 (16,1%) nello stadio 4 e 12 (13,8%) nello stadio 1. Sedici (18,4%) dei soggetti dello studio non erano immunosoppressi come definito da CD4 >25%, 19 (21,8%) erano moderatamente immunosoppressi e 52 (59,8%) erano gravemente immunosoppressi. Un terzo dei bambini con infezione da HIV presentava una qualche forma di malattia renale. In questo studio, la proteinuria persistente era più frequente tra i bambini con uno stadio clinico iniziale della malattia da HIV/AIDS.

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