Prüfung Und Verarbeitung Von Arzneidrogen: Erster Band: Chemische Prüfung
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Eine erfolgreiche Arzneipflanzentherapie kann nur unter der Voraus- setzung durchgeführt werden, da Drogen und Drogenzubereitungen einen Mindestgehalt und einen konstanten Gehalt an Wirkstoffen auf- weisen. Auch der Gewinnung von reinen Wirkstoffen aus Arzneidrogen geht eine Prüfung der Dröge auf den Wirkstoffgehalt voraus. Die Prüfung der Arzneidrogen durch Bestimmung des Wirkstoffgehaltes ist deshalb für die Therapie mit Arzneidrogen und deren Verarbeitung von grund- sätzlicher Bedeutung. Seitdem Wirkstoffe in den Drogen erkannt wur- den, war man bemüht, Methoden zu ihrer Bestimmung auszuarbeiten. Die chemische Bestimmung der speziellen \Virkstoffe von Arznei- drogen hat in den letzten Jahren durch Einführung neuer Methoden eine weitgehende Förderung erfahren. Vor allein durch Ausarbeiten von colo- rimetrischen Verfahren ist es möglich geworden, die Genauigkeit und Spezifität der Bestimmung zu erhöhen, Mikromethoden zu entwickeln und Wirkstoffe zu erfassen, deren Bestimmung durch gravimetrische oder ma analytische Methoden bisher nicht möglich gewesen ist. In Wirkstoff- gemischen gelang es teilweise, den'Hauptwirkstoff allein analytisch zu er- fassen und somit die Spezifität der Bestimmung zu erhöhen. Diese Ent- wicklung, die auch die Einführung der Adsorptionsanalyse, optischer Methoden und der Papierchromatographie einschlie t, ist noch in vollem Flu und wird die Prüfung der Arzneidrogen durch chemische Bestim- mung der Wirkstoffe auch weiterhin zu einem höheren Grad analytischer Genauigkeit führen. Wenn auch die Wirkstoffe zahlreicher Arzneidrogen genau bekannt sind, so gibt es auch solche, die sich nicht als chemisch einheitliche und genau charakterisierte Stoffe fassen lassen, sondern nur als Wirkstoff- gruppen und nur durch allgemeine Methoden bestimmt werden können.
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