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Quadruplex Nucleic Acids As Targets For Medicinal Chemistry by Stephen Neidle

Quadruplex Nucleic Acids As Targets For Medicinal Chemistry

by Stephen Neidle
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Book cover type: Hardcover
  • ISBN13: 9780128210178
  • Binding: Hardcover
  • Subject: N/A
  • Publisher: Academic Press
  • Publisher Imprint: Academic Press
  • Publication Date:
  • Pages: 564
  • Original Price: USD 175.0
  • Language: English
  • Edition: N/A
  • Item Weight: 921 grams
  • BISAC Subject(s): Chemistry / General

The realisation that human, animal, viral and bacterial genomes all contain over-representation of higher-order quadruplex structures in regulatory and other pharmacologically-useful regions, has led to a large number of studies aimed at exploiting this findings for therapeutic and diagnostic purposes. Quadruplex-binding small molecules are starting to be evaluated in human clinical trials.

Neidle, Stephen: - Stephen Neidle is an Emeritus Professor of Chemical Biology at University College London, where he has also been the Director of Research in the School of Pharmacy. He has published over 500 primary papers and reviews and is a principal inventor on 14 patent filings. He has also written and edited several books on nucleic acids and anti-cancer drugs.

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