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Química dos medicamentos e inovações terapêuticas by Chafaa, Fouad

Química dos medicamentos e inovações terapêuticas

by Fouad Chafaa
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Book cover type: Paperback
  • ISBN13: 9786202457255
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Edicoes Nosso Conhecimento
  • Publisher Imprint: Edicoes Nosso Conhecimento
  • Publication Date:
  • Pages: 72
  • Original Price: GBP 52.98
  • Language: Portuguese
  • Edition: N/A
  • Item Weight: 109 grams
  • BISAC Subject(s): Chemistry / General

A qu�mica terap�utica � uma disciplina essencial na interface entre a qu�mica e as ci�ncias biom�dicas. Desempenha um papel central na conce��o e compreens�o do mecanismo de a��o, bem como no estudo do destino dos f�rmacos no organismo. Permite uma an�lise aprofundada da estrutura dos ingredientes activos, a previs�o do seu metabolismo e a avalia��o das suas intera��es com alvos biol�gicos, como enzimas ou receptores. O dom�nio dos grupos funcionais, dos mecanismos de rea��o e das propriedades f�sico-qu�micas das mol�culas � essencial para prever a sua reatividade, biodisponibilidade e efic�cia terap�utica. A estereoqu�mica tamb�m desempenha um papel vital, uma vez que a atividade biol�gica de um f�rmaco depende frequentemente da sua configura��o espacial. Uma simples altera��o do arranjo tridimensional pode transformar uma mol�cula ativa num composto inativo ou mesmo t�xico. A qu�mica terap�utica representa, por conseguinte, uma verdadeira ponte entre os fundamentos te�ricos da qu�mica e as suas aplica��es pr�ticas no dom�nio da sa�de. Constitui uma base de conhecimentos essencial para qualquer abordagem inovadora da farmacologia, da investiga��o farmac�utica e do desenvolvimento de novas terapias.

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