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RNA Modification by Jonatha M. Gott

RNA Modification

by Jonatha M. Gott
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Book cover type: Hardcover
  • ISBN13: 9780123741554
  • Binding: Hardcover
  • Subject: N/A
  • Publisher: Academic Press
  • Publisher Imprint: Academic Press
  • Publication Date:
  • Pages: 480
  • Original Price: USD 225.0
  • Language: English
  • Edition: N/A
  • Item Weight: 776 grams
  • BISAC Subject(s): Life Sciences / Genetics & Genomics, Life Sciences / Molecular Biology, and Life Sciences / Biochemistry

The presence of modified nucleotides in cellular RNAs has been known for decades and over 100 distinct RNA modifications have been characterized to date. While the exact role of many of these modifications is still unclear, many are highly conserved across evolution and most contribute to the overall fitness of the organism. In recent years, new methods and bioinformatics approaches have been developed for the dissection of modification pathways and functions. These methods intersect a number of related fields, ranging from RNA processing to comparative genomics and systems biology. In addition, many of the techniques described in this volume have broad applicability, particularly in regards to the isolation, characterization, and reconstitution of ribonucleoprotein complexes, expanding the experimental repertoire available to all RNA researchers.

Gott, Jonatha M.: - Jonatha Gott works in the Center for RNA Molecular Biology at Case Western Reserve University, Cleveland, Ohio, USA.

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