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Separation Methods in Drug Synthesis and Purification by Klara Valko

Separation Methods in Drug Synthesis and Purification

by Klara Valko
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Book cover type: Paperback
  • ISBN13: 9780444640703
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Elsevier Science
  • Publisher Imprint: Elsevier Science
  • Publication Date:
  • Pages: 788
  • Original Price: USD 300.0
  • Language: English
  • Edition: 2nd Ed.
  • Item Weight: 1039 grams
  • BISAC Subject(s): Chemistry / Analytic, Chemistry / Organic, and Chemistry / Physical & Theoretical

Separation Methods in Drug Synthesis and Purification, Second Edition, Volume Eight, provides an updated on the analytical techniques used in drug synthesis and purification. Unlike other books on either separation science or drug synthesis, this volume combines the two to explain the basic principles and comparisons of each separation technique. New sections to this volume include enantiomer separation using capillary electrophoresis (CE) and capillary electro- chromatography, the computer simulation of chromatographic separation for accelerating method development, the application of chromatography and capillary electrophoresis used as surrogates for biological processes, and new developments in the established techniques of chromatography and preparative methods.

Valko, Klara: - Dr. Klára Valkó is an enthusiastic principal scientist and consultant supporting early drug discovery and lead optimization with over 22 years of experience. She has been an Honorary Professor at UCL School of Pharmacy since 2004, leading the Physchem/ADME module (London, UK) for Drug Discovery MSc. Her many contributions to the field include the development of biomimetic HPLC methods for high throughput measurements of serum albumin, glycoprotein and phospholipid binding, the invention of the Chromatographic Hydrophobicity Index for fast determination of compounds' lipophilicity using generic gradient reversed phase chromatography, and more.

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