Séroépidémiologie de la transmission transfusionnelle de Toxoplasma gondii, du CMV et du virus de la tuberculose
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La s�ro�pid�miologie des infections transmises par transfusion telles que Toxoplasma gondii, le cytom�galovirus (CMV) et le parvovirus B19 chez les donneurs de sang sains en Inde souligne un probl�me de sant� publique important, en particulier pour les personnes immunod�prim�es, les nouveau-n�s et les femmes enceintes. Des �tudes men�es dans diff�rentes r�gions de l'Inde r�v�lent que la s�ropr�valence des anticorps IgG de T. gondii chez les donneurs de sang se situe entre 20 et 25 % environ, ce qui indique une exposition pass�e, tandis qu'un pourcentage plus faible pr�sente une positivit� des IgM, ce qui sugg�re des infections r�centes. Le CMV pr�sente une s�ropr�valence particuli�rement �lev�e chez les donneurs de sang indiens, avec des taux de positivit� des IgG compris entre 90 % et 97 %, refl�tant une exposition ant�rieure g�n�ralis�e, tandis que la positivit� des IgM reste faible, ce qui indique moins d'infections r�centes. Les �tudes de s�ropr�valence du parvovirus B19 indiquent que les anticorps IgG sont pr�sents chez environ 27 % � 40 % des donneurs, ce qui indique une exposition ant�rieure, tandis que les anticorps IgM sont d�tect�s chez environ 1,4 % � 7,5 % des donneurs, ce qui indique des infections actuelles ou r�centes.
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