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Sickle cell anemia by Sudhir Rawlani

Sickle cell anemia

by Sudhir Rawlani
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Book cover type: Paperback
  • ISBN13: 9786209575273
  • Binding: Paperback
  • Subject: N/A
  • Publisher: LAP Lambert Academic Publishing
  • Publisher Imprint: LAP Lambert Academic Publishing
  • Publication Date:
  • Pages: 52
  • Original Price: GBP 38.19
  • Language: English
  • Edition: N/A
  • Item Weight: 82 grams
  • BISAC Subject(s): General

Sickle cell anemia is a hereditary blood disorder caused by a mutation in the β-globin gene, leading to formation of abnormal hemoglobin called HbS.Under low oxygen conditions, HbS polymerizes, causing red blood cells to become sickle-shaped, rigid, and fragile.These abnormal cells have a short lifespan (10-20 days) and can block small blood vessels.Key features: Chronic hemolytic anemia. Painful vaso-occlusive crises. Recurrent infections (due to functional asplenia). Delayed growth and organ damage (spleen, kidneys, lungs, brain).

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