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Spatially Variable Genes in Cancer: Development, Progression, and Treatment Response by Ramya Raghavan

Spatially Variable Genes in Cancer: Development, Progression, and Treatment Response

by Ramya Raghavan
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Book cover type: Paperback
  • ISBN13: 9798369377291
  • Binding: Paperback
  • Subject: N/A
  • Publisher: IGI Global
  • Publisher Imprint: IGI Global
  • Publication Date:
  • Pages: 606
  • Original Price: USD 540.0
  • Language: English
  • Edition: N/A
  • Item Weight: 1384 grams
  • BISAC Subject(s): Oncology / General

Spatial variable genes (SVGs) in cancer refer to genes that exhibit different expression levels or patterns across different regions or cells within a tumor. Cancer-associated fibroblasts (CAFs) are a crucial component of the tumor microenvironment (TME), playing a fundamental role in tumor progression, metastasis, and therapy response. Identifying and characterizing SVGs can reveal novel targets for cancer treatment. Combining spatial transcriptomics with other omics data can provide a more comprehensive picture of tumor biology. Spatially Variable Genes in Cancer: Development, Progression, and Treatment Response illuminates the heterogeneity within tumors, challenging the traditional one-size-fits-all approach. The chapters examine how SVGs influence tumor biology and pave the way for novel diagnostic and therapeutic approaches. Covering topics such as bioengineering, gene expression, and tumor initiation, this book is an excellent resource for academicians, researchers, students, oncologists, medical professionals, medical administrators, scientists, and more.

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