Stand Und Gegenstand Chirurgischer Forschung
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In kaum einem Bereich der Medizin sind experimentelle und klinische Forschung so eng miteinander verknüpft wie in der Chirurgie. Ange- fangen von Untersuchungen zu verschiedenen Naht- und Anastomo- senmethoden bis zu weitreichenden Verfahren der Herz-Lungen- Maschinenanwendung, der Organkonservierung und schlie lich der Organtransplantation sind die engen Verflechtungen von Experi- ment und klinischer Anwendung offensichtlich. Immer wenn experi- mentelle Grundlagen in die Klinik übertragen werden, müssen exakte Überprüfungen der erwarteten Ergebnisse mit ihren Auswir- kungen auf den Kranken in ihr Recht treten. Wie weit hier retro- spektive Untersuchungen ausreichen oder prospektiven Studien grundsätzlich der Vorrang gebührt, ist immer wieder Gegenstand der Diskussion. In einem ersten Teil werden diese und ähnliche Grundsatzfragen chirurgischer Forschung von verschiedenen Standpunkten aus einge- hend beleuchtet, gefolgt von speziellen Darstellungen exemplari- schen Charakters aus fast allen Bereichen der Chirurgie. Dabei konnte Vollständigkeit nicht angestrebt werden. Die Vielfalt der Aussagen lä t dennoch klare Konturen erkennen und gibt Richtun- gen für künftige Forschungen an. Es liegt in der Natur der Sache, da die Verflechtungen mit vielen Nachbardisziplinen deutlich werden. Georg Heberers besonderes Interesse galt stets der Grundlagen- forschung in der Chirurgie sowie der Pathophysiologie des opera- tiven Eingriffs und seiner Folgen. Es lag deshalb nahe, ihm zu sei- nem 65. Geburtstag ein Symposium zum Thema "Stand und Gegen- stand chirurgischer Forschung" zu widmen. Die dabei gehaltenen Vorträge bilden den Kern des nun vorliegenden Buches gleichen Titels. Mitaufgenommen wurden zahlreiche Einzelbeiträge seiner Schüler und Freunde aus speziellen Gebieten, damit die Breite chir- urgischer Forschung an einzelnen Beispielen sichtbar wird.
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