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Staphylococcus epidermidis et Biofilm by Anis Raddaoui

Staphylococcus epidermidis et Biofilm

by Anis Raddaoui
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Book cover type: Paperback
  • ISBN13: 9786209444807
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Editions Universitaires Europeennes
  • Publisher Imprint: Editions Universitaires Europeennes
  • Publication Date:
  • Pages: 76
  • Original Price: GBP 38.19
  • Language: French
  • Edition: N/A
  • Item Weight: 114 grams
  • BISAC Subject(s): Life Sciences / Microbiology

Ce document est une �tude approfondie sur le probl�me des infections nosocomiales li�es aux cath�ters veineux centraux, caus�es principalement par le biofilm de Staphylococcus epidermidis. Sa grande dangerosit� provient de sa capacit� � former un biofilm, une communaut� bact�rienne structur�e et encapsul�e dans une matrice protectrice. Ce biofilm conf�re � la bact�rie une tol�rance exceptionnelle aux antibiotiques et lui permet d'�chapper aux d�fenses du syst�me immunitaire, rendant les infections tr�s difficiles � traiter. L'ouvrage d�taille les m�canismes mol�culaires complexes r�gissant la formation de ce biofilm, en particulier le r�le cl� de l'op�ron ica et du polysaccharide. Face � ce d�fi clinique majeur, le texte passe �galement en revue les diff�rentes strat�gies de lutte (cath�ters impr�gn�s, inhibition de la communication bact�rienne, enzymes) et d�crit les mod�les exp�rimentaux, tant in vitro qu'in vivo, utilis�s pour �tudier ce biofilm et tester de nouvelles solutions th�rapeutiques.

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