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Structure-Based Drug Design by Pandi Veerapandian

Structure-Based Drug Design

by Pandi Veerapandian
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Book cover type: Hardcover
  • ISBN13: 9780824798697
  • Binding: Hardcover
  • Subject: N/A
  • Publisher: Taylor & Francis Inc
  • Publisher Imprint: CRC Press
  • Publication Date:
  • Pages: 664
  • Original Price: GBP 190.0
  • Language: English
  • Edition: N/A
  • Item Weight: 931 grams
  • BISAC Subject(s): Pharmacy

Introducing the most recent advances in crystallography, nuclear magnetic resonance, molecular modeling techniques, and computational combinatorial chemistry, this unique, interdisciplinary reference explains the application of three-dimensional structural information in the design of pharmaceutical drugs. Furnishing authoritative analyses by world-renowned experts, Structure-Based Drug Design discusses protein structure-based design in optimizing HIV protease inhibitors and details the biochemical, genetic, and clinical data on HIV-1 reverse transcriptase presents recent results on the high-resolution three-dimensional structure of the catalytic core domain of HIV-1 integrase as a foundation for divergent combination therapy focuses on structure-based design strategies for uncovering receptor antagonists to treat inflammatory diseases demonstrates a systematic approach to the design of inhibitory compounds in cancer treatment reviews current knowledge on the Interleukin-1 (IL-1) system and progress in the development of IL-1 modulators describes the influence of structure-based methods in designing capsid-binding inhibitors for relief of the common cold and much more

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