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Studies on Protein: RNA Complexes by Steffen Grimm

Studies on Protein: RNA Complexes

by Steffen Grimm
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Book cover type: Paperback
  • ISBN13: 9783639009477
  • Binding: Paperback
  • Subject: N/A
  • Publisher: VDM Verlag Dr. Mueller E.K.
  • Publisher Imprint: VDM Verlag Dr. Mueller E.K.
  • Publication Date:
  • Pages: 200
  • Original Price: GBP 40.67
  • Language: English
  • Edition: N/A
  • Item Weight: 273 grams
  • BISAC Subject(s): Life Sciences / Biochemistry

The central role of RNA in many cellular processes has created a high interest in the specific tasks RNA molecules and protein: RNA com-plexes perform in a cell. In this publication up-to-date experimental methods and protein: RNA interaction protocols were used to identify the native RNA binding motive and to characterize the key role of the protein ribosomal binding factor A(RbfA). To gain insights into the binding mode of RbfA to its target RNA, two RbfA constructs from Thermotoga maritima and Helicobacter pylori were employed. Comparison of the RbfA proteins with the published homologous structure from Escherichia coli, led to studies concerning the structural attributes between proteins from thermophilic and mesophilic sys-tems. The different chapters detail the biophysical and biochemical methods used to investigate the protein and protein: RNA structures and their function and the advances in understanding the biological processes in which the RbfA protein is involved in.

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