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Stymulacja optogenetyczna dwoma fotonami by Kamal Dhakal

Stymulacja optogenetyczna dwoma fotonami

by Kamal Dhakal
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Book cover type: Paperback
  • ISBN13: 9786208666200
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Wydawnictwo Nasza Wiedza
  • Publisher Imprint: Wydawnictwo Nasza Wiedza
  • Publication Date:
  • Pages: 64
  • Original Price: USD 38.0
  • Language: Polish
  • Edition: N/A
  • Item Weight: 100 grams
  • BISAC Subject(s): Life Sciences / Biochemistry

Stymulacja kom�rek, zwlaszcza neuron�w, ma duże znaczenie zar�wno dla podstawowego zrozumienia obwod�w neuronalnych, jak i leczenia klinicznego. Istniejące elektrodowe metody stymulacji są inwazyjne i niespecyficzne dla pojedynczych kom�rek. Niedawno, optyczna stymulacja ukierunkowanych neuron�w wyrażających bialka wrażliwe na światlo (opsyny) pojawila się jako wylaniająca się i potężna technika (Optogenetyka) w neuronauce. Ze względu na rozpraszanie i pochlanianie światla, stymulacja oparta na optogenetyce jest r�wnież ograniczona do obszar�w powierzchownych. Aby osiągnąc doglębną stymulację i efektywne dostarczanie światla, pomocna jest światlowodowa optogenetyka dwufotonowa. Podstawowy mechanizm wzbudzenia dwoma fotonami i jego analogia do wzbudzenia channelrhodpsin-2 zostaly om�wione w tej książce. Światlowodowa dwufotonowa optogenetyka umożliwi doglębną zlokalizowaną stymulację w celu badania i manipulowania obwodami neuronowymi z wysoką rozdzielczością przestrzenną. Dlatego też niniejsza książka rzuci nieco światla na dwufotonową stymulację optogenetyczną kom�rek i tkanek i może byc przydatna dla każdego zainteresowanego tą dziedziną.

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