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Superfícies bioativas e nanoestruturadas by Fufă, Mariana Oana Mihaela

Superfícies bioativas e nanoestruturadas

by Mariana Oana Mihaela Fufă , Alexandru Mihai Grumezescu
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Book cover type: Paperback
  • ISBN13: 9786209003189
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Edicoes Nosso Conhecimento
  • Publisher Imprint: Edicoes Nosso Conhecimento
  • Publication Date:
  • Pages: 104
  • Original Price: GBP 34.71
  • Language: Portuguese
  • Edition: N/A
  • Item Weight: 150 grams
  • BISAC Subject(s): General

Uma vez que a resist�ncia bacteriana amplificada est� a tornar-se um fen�meno preocupante, especialmente devido ao aumento das complica��es relatadas, os dispositivos m�dicos especializados que reduzem as taxas de infe��o s�o um campo de investiga��o m�dica importante e crucial. No futuro, o presente livro aborda uma dessas possibilidades, descrevendo um m�todo de otimiza��o de dispositivos m�dicos atrav�s da sua modifica��o com superf�cies nanoestruturadas que impedem o desenvolvimento de biofilmes bacterianos aderentes. Preparados pela t�cnica de evapora��o a laser pulsado assistida por matriz, revestimentos finos � base de nanopart�culas de prata com uma morfologia esf�rica cristalina e um di�metro m�dio inferior a 10 nm mostraram resultados encorajadores, �teis no campo biom�dico tamb�m devido � sua distribui��o seletiva nos tecidos, como demonstrado durante testes in vitro e in vivo. Estas camadas nanoestruturadas que revestem a superf�cie dos cateteres m�dicos reduzem significativamente a ader�ncia de bact�rias e a forma��o de biofilmes, sendo candidatas perfeitas para o desenvolvimento de novas terapias anti-infecciosas. Os resultados experimentais apresentados neste livro apresentam uma t�cnica original que pode ser utilizada para otimizar dispositivos m�dicos explorat�rios e prot�ticos de uso generalizado.

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