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Synteza, spektroskopia, aktywnośc biologiczna mieszanych kompleksów ligandów by Hanan Okla

Synteza, spektroskopia, aktywnośc biologiczna mieszanych kompleksów ligandów

by Hanan Okla
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Book cover type: Paperback
  • ISBN13: 9786208806842
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Wydawnictwo Nasza Wiedza
  • Publisher Imprint: Wydawnictwo Nasza Wiedza
  • Publication Date:
  • Pages: 172
  • Original Price: GBP 60.81
  • Language: Polish
  • Edition: N/A
  • Item Weight: 236 grams
  • BISAC Subject(s): Chemistry / Inorganic

Nowy ligand zasadowy Schiffa (HL) pochodzący z kondensacji 2-karboksyaldehydu chinolinowego z 2-aminofenolem i jego mieszane kompleksy ligandowe Cr(III), Mn(II), Fe(III), Co(II), Ni(II), Cu(II), Zn(II) i Cd(II) z 2,2'-bipirydyną/1, 10-fenantroliny jako liganda drugorzędowego zostaly zsyntetyzowane i scharakteryzowane za pomocą analiz elementarnych, badań spektroskopowych (IR, widma masowe, 1H NMR, UV-vis, podatnośc magnetyczna i odbicie ciala stalego), przewodnictwa molowego, dyfrakcji rentgenowskiej, ESR i badań termicznych. Parametry kinetyczne i termodynamiczne obliczono metodami Coatsa-Redferna i Horowitza-Metzgera. Ponadto, ligand zasadowy Schiffa i jego mieszane kompleksy ligandowe zostaly przebadane przeciwko bakteriom Gram-dodatnim (Streptococcus pneumoniae i Bacillis subtilis) i Gram-ujemnym (Pseudomonas aeruginosa i Escherichia coli). Aktywnośc przeciwgrzybicza zostala przeprowadzona przeciwko (Aspergillus fumigatus i Candida albicans). Ponadto, aktywnośc przeciwnowotworowa ligandu Schiffa i jego mieszanych kompleks�w ligandowych zostala r�wnież przetestowana przeciwko linii kom�rkowej raka piersi (MCF-7) i linii kom�rkowej raka okrężnicy (HCT-116).

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