Toxin-Antitoxin-System bei Enterococcus

Name: Toxin-Antitoxin-System bei Enterococcus
Brand: Verlag Unser Wissen
SKU: 9786630077544
Price: 7342.0 INR
Availability: InStock

by Nourkhoda Sadeghifard

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ISBN13: 9786630077544
Binding: Paperback
Subject: N/A
Publisher: Verlag Unser Wissen
Publisher Imprint: Verlag Unser Wissen
Publication Date: May 23, 2026
Pages: 100
Original Price: GBP 58.0
Language: German
Edition: N/A
Item Weight: 146 grams
BISAC Subject(s): Life Sciences / Microbiology

About The Book

Das Toxin-Antitoxin-System (TA-System) ist ein Regulationssystem, bei dem zwei Gens�tze das Toxin und das entsprechende Antitoxin kodieren. TA-Systeme wurden erstmals Mitte der 80er Jahre beschrieben. Das TA-System kann auf einem Chromosom oder einem Plasmid liegen. In allen TA-Systemen ist das Antitoxin instabil und das Toxin stabil. In TA-Systemen, die auf einem Plasmid basieren, entstehen Tochterzellen, die das Plasmid erben. Die Tochterzellen, die das Plasmid mit dem TA-System nicht erben k�nnen, werden abget�tet. Aufgrund des Abbaus des Antitoxins t�tet das stabile Toxin die Zelle ab. Dies wird als Post-Segregation-Killing bezeichnet. Enterokokken sind grampositive Kokken, fakultativ anaerob und geh�ren zu den Milchs�urebakterien der Gattung Firmicutes. Enterokokken sind in der Lage, einer Vielzahl von widrigen Bedingungen zu widerstehen, wie z. B. unterschiedlichen pH-Werten, hohen NaCl-Konzentrationen und einem Temperaturbereich von 5 C bis 65 C. E. faecalis und E. faecium sind zwei der wichtigsten kommensalen Arten im menschlichen Darm. Die wichtigsten durch Enterokokken verursachten Infektionen sind Harnwegsinfektionen, Gallenwegsinfektionen, Meningitis, Endokarditis, Divertikulitis und Bakteri�mie.

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