Um inquérito prospetivo e biomédico na Argélia
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Este artigo apresenta uma investiga��o biom�dica prospetiva sobre o desenvolvimento de uma pel�cula de bionanocomp�sito sob a forma de c�psulas orais para tratar �lceras faciais causadas por traumas psicol�gicos. As �lceras faciais s�o uma doen�a em crescimento, frequentemente associada a traumas f�sicos, mas os factores psicol�gicos exigem um tratamento inovador. Os componentes da pel�cula-c�psula s�o essenciais para a formula��o eficaz do medicamento. Os principais componentes do envelope bionanocomp�sito incluem nano-celulose, quitosano, PCL, PEG e sorbitol. As c�psulas duras s�o melhor fabricadas com estes materiais, que oferecem estabilidade e biodegradabilidade. As c�psulas moles s�o mais complexas de fabricar devido � compatibilidade qu�mica. Levant�mos a hip�tese de uma liga��o entre o trauma psicol�gico e as �lceras faciais, embora esta n�o tenha sido claramente estabelecida. Os factores psicol�gicos podem influenciar o estado da pele facial na presen�a de certas bact�rias nasais. S�o necess�rios estudos cl�nicos para verificar a hip�tese, uma vez validadas as propriedades f�sico-qu�micas, toxicol�gicas e antimicrobianas do rem�dio proposto.
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