Uremic Toxins and Organ Failure

Name: Uremic Toxins and Organ Failure
Brand: Springer
SKU: 9789811577956
Price: 7345.0 INR
Availability: InStock

by Hideyuki Saito

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ISBN13: 9789811577956
Binding: Paperback
Subject: N/A
Publisher: Springer
Publisher Imprint: Springer
Publication Date: October 14, 2021
Pages: 180
Original Price: EUR 99.99
Language: English
Edition: 2020
Item Weight: 327 grams
BISAC Subject(s): Nephrology, Gastroenterology, and Cardiology

About The Book

From the Back Cover
This book describes the latest research on the gut-kidney axis of ureic solutes; the toxico-pathological mechanisms of uremic toxin-induced organ failure, including kidney and cardiovascular tissue; and the preventive therapeutic strategies for uremia and related organ failure associated with kidney injuries and diseases. Retained uremic toxins cause a variety of symptoms, such as hypertension, fatigue, renal anemia, osteoporosis and neurologic impairment, which are apparent in chronic kidney disease (CKD) patients. The human gastrointestinal tract contains trillions of microorganisms, referred to as gut microbiota, which support the host metabolism by producing nutrients, such as vitamins and short-chain fatty acids. However, they also produce various harmful uremic toxins that show renal and cardiovascular toxicity, and correlate with an increased mortality in CKD patients. The composition and balance of gut microbiota are associated with the accumulation of uremic toxins and the pathophysiology of CKD, and as such are being considered for a novel therapeutic strategy.

About The Author

Hideyuki Saito

Department of Pharmacy, Kumamoto University Hospital & Department of Clinical Pharmaceutical Sciences, Kumamoto University Graduate School of Life Sciences, Kumamoto University

Honjo, Chuo-ku, Kumamoto, Japan

Email: saitohide@kuh.kumamoto-u.ac.jp

Takaaki Abe

Division of Nephrology, Endocrinology, and Vascular Medicine, Department of Medicine

Tohoku University Graduate School of Medicine

Seiryo-cho, Aoba-ku, Sendai, Japan

Email: takaabe@med.tohoku.ac.jp

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