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Vaccine Adjuvants by Charles J. Hackett, Donald A. Harn Jr

Vaccine Adjuvants

by Charles J. Hackett , Donald A. Harn Jr
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Book cover type: Hardcover
  • ISBN13: 9780896038929
  • Binding: Hardcover
  • Subject: N/A
  • Publisher: Humana
  • Publisher Imprint: Humana
  • Publication Date:
  • Pages: 284
  • Original Price: GBP 129.99
  • Language: English
  • Edition: 2006
  • Item Weight: 595 grams
  • BISAC Subject(s): Pharmacology

A cutting-edge review of the major research areas of adjuvant discovery, design, development, and use. The authors lay down a rational basis for vaccine adjuvant function and analyze a number of significantly distinct adjuvant-active molecules to illuminate the principles of their function and use. The focus is on specific receptor-ligand interactions, including the molecular features needed for a compound to possess adjuvant activity. The critical interface zone between the innate and adaptive immune systems is also analyzed to show how adjuvants exert their effects on T- and B-cell activation. Additional chapters address the possibility of tailoring adjuvants to yield optimally safe and effective responses.

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