Veränderungen Des Wasser- Und Elektrolythaushaltes Durch Osmotherapeutika
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Die Osmotherapie, d. h. die therapeutische Anwendung haupts�chlich hypertoner Infusionsl�sungen mit dem Ziel, das Wassergleichgewicht des Organismus zu beeinflussen, hat in den letzten Jahren in vielen Bereichen der klinischen Medizin eine zunehmende Bedeutung erlangt. Es sei hier nur an die Behandlung des akuten Him�dems durch osmotherapeutische Ma nahmen erinnert. Aber auch die Intensivtherapie konfrontiert den behandelnden Arzt st�ndig mit Fragen der Anwendung hypertoner In- fusionsl�sungen. In allen diesen F�llen ist es vor allem der Anaesthesist, von dem direkt bei seiner klinischen T�tigkeit oder indirekt als Konsiliarius besondere Kenntnisse auf diesem Gebiet erwartet werden. F�r ihn war es bisher jedoch gar nicht leicht, sich �ber die theoretischen Grundlagen und die praktische Anwendung der Osmotherapie umfassend zu informieren. Die vorliegende Monographie k�nnte ihm hierbei eine gro e Hilfe sein. Mit der wachsenden Bedeutung der hypertonen Osmotherapie in vielen Bereichen der klinischen Medizin ergab sich immer st�rker das Bed�rfnis, einen Weg zur quantitativen Beurteilung der Wirksamkeit verschiedener Therapeutika zu finden. Eine kaum zu �bersehende Zahl von Original- mitteilungen und zusammenfassenden Darstellungen besch�ftigen sich mit dieser Frage. In fast allen Arbeiten wird jedoch jeweils nur ein be- stimmter Teilaspekt des Problems erfa t. Der Autor hat sich daher die Aufgabe gestellt, an einem einheitlichen Kollektiv unter standardisierten Bedingungen alle diejenigen Daten gemeinsam zu erfassen, die f�r die Beurteilung der hypertonen Osmotherapie von Bedeutung sind. Insbe- sondere stellt er die Frage 1. nach den Ver�nderungen der zirkulierenden Blutmenge und Blutzusammensetzung sowie 2. nach den Wasser- und Elek-trolytverlusten, die unter der hypertonen Therapie auftreten.
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